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HDL mimetic peptide ATI-5261 forms an oligomeric assembly in solution that dissociates to monomers upon dilution
ATI-5261 is a 26-mer peptide that stimulates cellular cholesterol efflux with high potency. This peptide displays high aqueous solubility, despite having amphipathic α-helix structure and a broad non-polar surface. These features suggested to us that ATI-5261 may adopt a specific form in solution, h...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100537/ https://ncbi.nlm.nih.gov/pubmed/21476522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2002955 |
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