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Active targeting of RGD-conjugated bioreducible polymer for delivery of oncolytic adenovirus expressing shRNA against IL-8 mRNA

Even though oncolytic adenovirus (Ad) has been highlighted in the field of cancer gene therapy, transductional targeting and immune privilege still remain difficult challenges. The recent reports have noted the increasing tendency of adenoviral surface shielding with polymer to overcome the limits o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Jaesung, Nam, Hye Yeong, Kim, Tae-il, Kim, Pyung-Hwan, Ryu, Jihoon, Yun, Chae-Ok, Kim, Sung Wan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100416/
https://ncbi.nlm.nih.gov/pubmed/21531456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.03.084
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