Voltage-Gated Ion Channel Dysfunction Precedes Cardiomyopathy Development in the Dystrophic Heart

BACKGROUND: Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is associated with severe cardiac complications including cardiomyopathy and cardiac arrhythmias. Recent research suggests that impaired voltage-gated ion channels in dystrophic cardiomyocytes accompany cardia...

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Hoofdauteurs: Koenig, Xaver, Dysek, Sandra, Kimbacher, Stefanie, Mike, Agnes K., Cervenka, Rene, Lukacs, Peter, Nagl, Katrin, Dang, Xuan B., Todt, Hannes, Bittner, Reginald E., Hilber, Karlheinz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100353/
https://ncbi.nlm.nih.gov/pubmed/21677768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020300
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