Lack of the Receptor for Advanced Glycation End-Products Attenuates E. coli Pneumonia in Mice

BACKGROUND: The receptor for advanced glycation end-products (RAGE) has been suggested to modulate lung injury in models of acute pulmonary inflammation. To study this further, model systems utilizing wild type and RAGE knockout (KO) mice were used to determine the role of RAGE signaling in lipopoly...

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Main Authors: Ramsgaard, Lasse, Englert, Judson M., Manni, Michelle L., Milutinovic, Pavle S., Gefter, Julia, Tobolewski, Jacob, Crum, Lauren, Coudriet, Gina M., Piganelli, Jon, Zamora, Ruben, Vodovotz, Yoram, Enghild, Jan J., Oury, Tim D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100338/
https://ncbi.nlm.nih.gov/pubmed/21629785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020132
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