Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs

BACKGROUND: Exosomes or secreted bi-lipid vesicles from human ESC-derived mesenchymal stem cells (hESC-MSCs) have been shown to reduce myocardial ischemia/reperfusion injury in animal models. However, as hESC-MSCs are not infinitely expansible, large scale production of these exosomes would require...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chen, Tian Sheng, Arslan, Fatih, Yin, Yijun, Tan, Soon Sim, Lai, Ruenn Chai, Choo, Andre Boon Hwa, Padmanabhan, Jayanthi, Lee, Chuen Neng, de Kleijn, Dominique PV, Lim, Sai Kiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100248/
https://ncbi.nlm.nih.gov/pubmed/21513579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-47
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados