Flavonoids targeting of IκB phosphorylation abrogates carcinogen-induced MMP-9 and COX-2 expression in human brain endothelial cells

Brain endothelial cells play an essential role as structural and functional components of the blood–brain barrier (BBB). Increased BBB breakdown and brain injury are associated with neuroinflammation and are thought to trigger mechanisms involving matrix metalloproteinase upregulation. Emerging evid...

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Detalhes bibliográficos
Main Authors: Tahanian, Elizabeth, Sanchez, Luis Arguello, Shiao, Tze Chieh, Roy, René, Annabi, Borhane
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100225/
https://ncbi.nlm.nih.gov/pubmed/21625419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S19931
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