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Crosstalk Between PKA and Epac Regulates the Phenotypic Maturation and Function of Human Dendritic Cells
The cAMP-dependent signaling pathways that orchestrate dendritic cell (DC) maturation remain to be defined in detail. While cAMP was previously thought to signal exclusively through PKA, it is now clear that cAMP also activates Epac, a second major cAMP effector. Whether cAMP signaling via PKA is su...
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Auteurs principaux: | , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2010
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100203/ https://ncbi.nlm.nih.gov/pubmed/20729327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903066 |
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