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Crosstalk Between PKA and Epac Regulates the Phenotypic Maturation and Function of Human Dendritic Cells

The cAMP-dependent signaling pathways that orchestrate dendritic cell (DC) maturation remain to be defined in detail. While cAMP was previously thought to signal exclusively through PKA, it is now clear that cAMP also activates Epac, a second major cAMP effector. Whether cAMP signaling via PKA is su...

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Détails bibliographiques
Auteurs principaux: Garay, Jone, D’Angelo, June A., Park, YongKeun, Summa, Christopher M., Aiken, Martha L., Morales, Eric, Badizadegan, Kamran, Fiebiger, Edda, Dickinson, Bonny L.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100203/
https://ncbi.nlm.nih.gov/pubmed/20729327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903066
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