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Crosstalk Between PKA and Epac Regulates the Phenotypic Maturation and Function of Human Dendritic Cells

The cAMP-dependent signaling pathways that orchestrate dendritic cell (DC) maturation remain to be defined in detail. While cAMP was previously thought to signal exclusively through PKA, it is now clear that cAMP also activates Epac, a second major cAMP effector. Whether cAMP signaling via PKA is su...

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Detalhes bibliográficos
Main Authors: Garay, Jone, D’Angelo, June A., Park, YongKeun, Summa, Christopher M., Aiken, Martha L., Morales, Eric, Badizadegan, Kamran, Fiebiger, Edda, Dickinson, Bonny L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100203/
https://ncbi.nlm.nih.gov/pubmed/20729327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903066
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