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Free energy of nascent-chain folding in the translocon

During their synthesis many water-soluble proteins and nearly all membrane proteins transit through a protein-conducting channel in the membrane, the Sec translocon, from where they are inserted into the lipid bilayer. Increasing evidence indicates that folding of the nascent protein begins already...

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Bibliografische gegevens
Hoofdauteurs: Gumbart, James, Chipot, Christophe, Schulten, Klaus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100187/
https://ncbi.nlm.nih.gov/pubmed/21524073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2019299
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