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Toward Fulfilling the Promise of Molecular Medicine in Fragile X Syndrome

Fragile X syndrome (FXS) is the most common inherited form of mental retardation and a leading known cause of autism. It is caused by loss of expression of the fragile X mental retardation protein (FMRP), an RNA-binding protein that negatively regulates protein synthesis. In neurons, multiple lines...

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Bibliographic Details
Main Authors: Krueger, Dilja D., Bear, Mark F.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100156/
https://ncbi.nlm.nih.gov/pubmed/21090964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-061109-134644
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