Improvement of Foreign-Protein Production in Aspergillus niger var. awamori by Constitutive Induction of the Unfolded-Protein Response

Unfolded-protein response (UPR) denotes the upregulation of endoplasmic reticulum (ER)-resident chaperone and foldase genes and numerous other genes involved in secretory functions during the accumulation of unfolded proteins into the ER. Overexpression of individual foldases and chaperones has been...

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Bibliographic Details
Main Authors: Valkonen, Mari, Ward, Michael, Wang, Huaming, Penttilä, Merja, Saloheimo, Markku
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Physiology and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC309985/
https://ncbi.nlm.nih.gov/pubmed/14660339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.12.6979-6986.2003
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