Targeting Methanopterin Biosynthesis To Inhibit Methanogenesis

This paper describes the design, synthesis, and successful employment of inhibitors of 4-(β-d-ribofuranosyl)aminobenzene-5′-phosphate (RFA-P) synthase, which catalyzes the first committed step in the biosynthesis of methanopterin, to specifically halt the growth of methane-producing microbes. RFA-P...

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Autors principals: Dumitru, Razvan, Palencia, Hector, Schroeder, Scott D., DeMontigny, Bree A., Takacs, James M., Rasche, Madeline E., Miner, Jess L., Ragsdale, Stephen W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Physiology and Biotechnology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC309974/
https://ncbi.nlm.nih.gov/pubmed/14660371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.12.7236-7241.2003
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