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Targeting Methanopterin Biosynthesis To Inhibit Methanogenesis

This paper describes the design, synthesis, and successful employment of inhibitors of 4-(β-d-ribofuranosyl)aminobenzene-5′-phosphate (RFA-P) synthase, which catalyzes the first committed step in the biosynthesis of methanopterin, to specifically halt the growth of methane-producing microbes. RFA-P...

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Publicado no:Appl Environ Microbiol
Principais autores: Dumitru, Razvan, Palencia, Hector, Schroeder, Scott D., DeMontigny, Bree A., Takacs, James M., Rasche, Madeline E., Miner, Jess L., Ragsdale, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Physiology and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309974/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14660371/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.12.7236-7241.2003
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