Mitogen-activated Protein Kinase Kinase 1 (MEK1) Stabilizes MyoD through Direct Phosphorylation at Tyrosine 156 During Myogenic Differentiation

Previously, we reported that mitogen-activated protein kinase kinase 1 (MEK1) activated in the mid-stage of skeletal muscle differentiation promotes myogenic differentiation. To elucidate the molecular mechanism, we investigated an activity of MEK1 for MyoD. Activated MEK1 associates with MyoD in th...

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Bibliographic Details
Main Authors: Jo, Chulman, Cho, Sun-Jung, Jo, Sangmee Ahn
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099706/
https://ncbi.nlm.nih.gov/pubmed/21454680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225128
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