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Fibroblast Growth Factor Receptor-3 (FGFR-3) Regulates Expression of Paneth Cell Lineage-specific Genes in Intestinal Epithelial Cells through both TCF4/β-Catenin-dependent and -independent Signaling Pathways

Fibroblast growth factor receptor-3 (FGFR-3) expression in the developing intestine is restricted to the undifferentiated epithelial cells within the lower portion of the crypt. We previously showed that mice lacking functional FGFR-3 have a significant decrease in the number of Paneth cells in the...

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Detalhes bibliográficos
Main Authors: Brodrick, Brooks, Vidrich, Alda, Porter, Edith, Bradley, Leigh, Buzan, Jenny M., Cohn, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099668/
https://ncbi.nlm.nih.gov/pubmed/21388956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.229252
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