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The molecular mechanisms of drug resistance in single-step and multi-step drug-selected cancer cells
Multidrug resistance (MDR) remains one of the key determinants in chemotherapeutic success of cancer patients. Often, acquired resistance is mediated by the overexpression of ATP-binding cassette (ABC) drug transporters. To study the mechanisms involved in the MDR phenotype, investigators have gener...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099236/ https://ncbi.nlm.nih.gov/pubmed/19949921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-416-6_5 |
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