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METABOLIC STABILITY OF 6,7-DIALKOXY-4-(2-, 3- AND 4-[(18)F]FLUOROANILINO)QUINAZOLINES, POTENTIAL EGFR IMAGING PROBES

Epidermal growth factor receptors (EGFR), upregulated in many tumor types, have been a target for therapeutic development and molecular imaging. The objective of this study was to evaluate the distribution and metabolic characteristics of fluorine-18 labeled anilinoquinazolines as potential imaging...

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Detalhes bibliográficos
Main Authors: Vasdev, Neil, Dorff, Peter N., O’Neil, James P., Chin, Frederick T., Hanrahan, Stephen, VanBrocklin, Henry F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099137/
https://ncbi.nlm.nih.gov/pubmed/21478021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.03.032
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