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Mitochondrial Avid Radioprobes. Preparation and Evaluation of 7′(Z)-[(125)I]Iodorotenone and 7′(Z)-[(125)I]Iodorotenol

The loss of mitochondrial function has been implicated in a number of maladies such as Huntington’s Disease, Parkinson’s Disease, cancer and cardiovascular disease. The objective of this research was to develop a radiolabeled mitochondrial probe. Two tracers, 7′-Z-iodorotenol and 7′-Z-iodorotenone,...

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Detalhes bibliográficos
Main Authors: VanBrocklin, Henry F., Hanrahan, Stephen M., Enas, Joel D., Nandanan, Erathodiyil, O’Neil, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852529/
https://ncbi.nlm.nih.gov/pubmed/17210467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2006.10.005
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