Loss of visceral pain following colorectal distension in an endothelin-3 deficient mouse model of Hirschsprung's disease

ABSTRACT: Endothelin peptides and their endogenous receptors play a major role in nociception in a variety of different organs. They also play an essential role in the development of the enteric nervous system. Mice with deletions of the endothelin-3 gene (lethal spotted mice, ls/ls) develop congeni...

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Autores principales: Zagorodnyuk, Vladimir P, Kyloh, Melinda, Nicholas, Sarah, Peiris, Heshan, Brookes, Simon J, Chen, Bao Nan, Spencer, Nick J
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2011
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099024/
https://ncbi.nlm.nih.gov/pubmed/21320883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.202820
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