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Irritating channels: the case of TRPA1

Transient receptor potential (TRP) channels have been extensively studied over the past years. Yet, in most cases, the gating mechanisms of these polymodal cation channels still remain a puzzle. Using the nociceptive channel TRPA1 as an example, we discuss the role of dynamic regulation of the pore...

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Autori principali: Nilius, Bernd, Prenen, Jean, Owsianik, Grzegorz
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099014/
https://ncbi.nlm.nih.gov/pubmed/21078588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.200717
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