Llwytho...

Identification, in vitro activity and mode of action of Phosphoinositide-dependent-1 kinase inhibitors as antifungal molecules

Although protein kinases have recently emerged as important drug targets, the anti-infective potential of protein kinase inhibitors has not been developed extensively. We identified the mammalian PDK1 inhibitor KP-372-1 as a potent antifungal molecule with activity against yeast and fungal biofilms...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Baxter, Bonnie K., DiDone, Louis, Oga, Duana, Schor, Stanford, Krysan, Damian J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098953/
https://ncbi.nlm.nih.gov/pubmed/21294551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100399x
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