Female X-chromosome mosaicism for NOX2 deficiency presents unique inflammatory phenotype and improves outcome in polymicrobial sepsis

Cellular X chromosome mosaicism, which is unique to females may be advantageous during pathophysiological challenges as compared to the single X chromosome machinery of males and may also contribute to gender dimorphism in the inflammatory response. We tested the hypothesis whether cellular mosaicis...

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Bibliographic Details
Main Authors: Chandra, Rachna, Federici, Stephanie, Németh, Zoltán H., Horváth, Béla, Pacher, Pál, Haskó, György, Deitch, Edwin A., Spolarics, Zoltán
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098917/
https://ncbi.nlm.nih.gov/pubmed/21502376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100205
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