TRAIL-R4 Promotes Tumor Growth and Resistance to Apoptosis in Cervical Carcinoma HeLa Cells through AKT

BACKGROUND: TRAIL/Apo2L is a pro-apoptotic ligand of the TNF family that engages the apoptotic machinery through two pro-apoptotic receptors, TRAIL-R1 and TRAIL-R2. This cell death program is tightly controlled by two antagonistic receptors, TRAIL-R3 and TRAIL-R4, both devoid of a functional death d...

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Bibliografische gegevens
Hoofdauteurs: Lalaoui, Najoua, Morlé, Aymeric, Mérino, Delphine, Jacquemin, Guillaume, Iessi, Elisabetta, Morizot, Alexandre, Shirley, Sarah, Robert, Bruno, Solary, Eric, Garrido, Carmen, Micheau, Olivier
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098831/
https://ncbi.nlm.nih.gov/pubmed/21625476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019679
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