RNAi-based Therapeutics Targeting Survivin and PLK1 for Treatment of Bladder Cancer

Harnessing RNA interference (RNAi) to silence aberrant gene expression is an emerging approach in cancer therapy. Selective inhibition of an overexpressed gene via RNAi requires a highly efficacious, target-specific short interfering RNA (siRNA) and a safe and efficient delivery system. We have deve...

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Bibliographische Detailangaben
Hauptverfasser: Seth, Shaguna, Matsui, Yoshiyuki, Fosnaugh, Kathy, Liu, Yan, Vaish, Narendra, Adami, Roger, Harvie, Pierrot, Johns, Rachel, Severson, Gregory, Brown, Tod, Takagi, Akihide, Bell, Susan, Chen, Yan, Chen, Feng, Zhu, Tianying, Fam, Renata, Maciagiewicz, Iwona, Kwang, Erin, McCutcheon, Michael, Farber, Ken, Charmley, Patrick, Houston Jr., Michael E, So, Alan, Templin, Michael V, Polisky, Barry
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098637/
https://ncbi.nlm.nih.gov/pubmed/21364537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.21
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