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Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1
Apoptosis provoked by glucose shortage in dividing T cells is mediated via the BH3-only protein Noxa and inhibition of its binding partner Mcl-1. It is unknown how signals from cellular metabolism can affect the balance between Mcl-1 and Noxa and to what extent other Bcl-2 members are involved in th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098366/ https://ncbi.nlm.nih.gov/pubmed/21516346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-011-0599-8 |
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