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Multiple testing of treatment-effect modifying biomarkers in a randomized clinical trial with a survival endpoint
The recent revolution in genomics and the advent of targeted therapies have increased interest in biomarker-defined subgroups of patients who respond to therapy or exhibit specific toxicities. Such biomarker-defined subgroups are also being investigated for non-targeted therapies (e.g. chemotherapy...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098305/ https://ncbi.nlm.nih.gov/pubmed/21344471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4022 |
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