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Multiple testing of treatment-effect modifying biomarkers in a randomized clinical trial with a survival endpoint

The recent revolution in genomics and the advent of targeted therapies have increased interest in biomarker-defined subgroups of patients who respond to therapy or exhibit specific toxicities. Such biomarker-defined subgroups are also being investigated for non-targeted therapies (e.g. chemotherapy...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Michiels, Stefan, Potthoff, Richard F., George, Stephen L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098305/
https://ncbi.nlm.nih.gov/pubmed/21344471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4022
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