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Dynamics of the STAT3 Transcription Factor: Nuclear Import Dependent on Ran and Importin-β1

The signal transducer and activator of transcription-3 (STAT3) induces transcription of genes that control differentiation, inflammation, proliferation, and tumor cell invasion. Cytokines such as interleukin-6 and interferon stimulate the specific tyrosine phosphorylation of STAT3, which confers its...

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Detalhes bibliográficos
Main Authors: Cimica, Velasco, Chen, Hui-Chen, Iyer, Janaki K., Reich, Nancy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098288/
https://ncbi.nlm.nih.gov/pubmed/21625522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020188
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