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Highly frequent promoter methylation and PIK3CA amplification in non-small cell lung cancer (NSCLC)

BACKGROUND: Lung cancer is the leading cause of cancer-related death worldwide. Genetic and epigenetic alterations have been identified frequently in lung cancer, such as promoter methylation, gene mutations and genomic amplification. However, the interaction between genetic and epigenetic events an...

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Detalhes bibliográficos
Main Authors: Ji, Meiju, Guan, Haixia, Gao, Cuixia, Shi, Bingyin, Hou, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098185/
https://ncbi.nlm.nih.gov/pubmed/21507233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-147
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