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Highly frequent promoter methylation and PIK3CA amplification in non-small cell lung cancer (NSCLC)

BACKGROUND: Lung cancer is the leading cause of cancer-related death worldwide. Genetic and epigenetic alterations have been identified frequently in lung cancer, such as promoter methylation, gene mutations and genomic amplification. However, the interaction between genetic and epigenetic events an...

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Hlavní autoři: Ji, Meiju, Guan, Haixia, Gao, Cuixia, Shi, Bingyin, Hou, Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098185/
https://ncbi.nlm.nih.gov/pubmed/21507233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-147
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