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Armoring CRAds with p21/Waf-1 shRNAs: the next generation of oncolytic adenoviruses
Conditionally replicating adenoviruses (CRAds) represent a promising modality for the treatment of neoplastic diseases, including Prostate Cancer. Selectively replicating viruses can be generated by placing a tissue or cancer-specific promoter upstream of one or more of the viral genes required for...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098117/ https://ncbi.nlm.nih.gov/pubmed/20448671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2010.15 |
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