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Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles

BACKGROUND: Enzymes belonging to acyl:CoA synthetase (ACS) superfamily activate wide variety of substrates and play major role in increasing the structural and functional diversity of various secondary metabolites in microbes and plants. However, due to the large sequence divergence within the super...

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Autors principals: Khurana, Pankaj, Gokhale, Rajesh S, Mohanty, Debasisa
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098103/
https://ncbi.nlm.nih.gov/pubmed/20105319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-57
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