Glioma cancer stem cells induce immunosuppressive macrophages/microglia

Macrophages (MΦs)/microglia that constitute the dominant tumor-infiltrating immune cells in glioblastoma are recruited by tumor-secreted factors and are induced to become immunosuppressive and tumor supportive (M2). Glioma cancer stem cells (gCSCs) have been shown to suppress adaptive immunity, but...

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Bibliografiske detaljer
Main Authors: Wu, Adam, Wei, Jun, Kong, Ling-Yuan, Wang, Yongtao, Priebe, Waldemar, Qiao, Wei, Sawaya, Raymond, Heimberger, Amy B.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098021/
https://ncbi.nlm.nih.gov/pubmed/20667896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq082
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