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Glioma cancer stem cells induce immunosuppressive macrophages/microglia
Macrophages (MΦs)/microglia that constitute the dominant tumor-infiltrating immune cells in glioblastoma are recruited by tumor-secreted factors and are induced to become immunosuppressive and tumor supportive (M2). Glioma cancer stem cells (gCSCs) have been shown to suppress adaptive immunity, but...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Oxford University Press
2010
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098021/ https://ncbi.nlm.nih.gov/pubmed/20667896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq082 |
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