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Synthesis of C1–C20 and C21–C40 fragments of tetrafibricin

Efficient syntheses of suitably functionalized top and bottom fragments of tetrafibricin are described. The bottom fragment is prepared by two consecutive Kocienski-Julia couplings, while the top fragment synthesis features a dithiane alkylation and a Horner-Wadsworth-Emmons reaction.

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Detalles Bibliográficos
Autores principales: Gudipati, Venugopal, Curran, Dennis P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097483/
https://ncbi.nlm.nih.gov/pubmed/21603053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2011.01.086
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