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Fluorous Mixture Synthesis of Four Stereoisomers of the C21–C40 Fragment of Tetrafibricin

Four stereoisomers of the C21–C40 fragment are synthesized in a single exercise with the aid of fluorous tagging to encode configurations at C37 and C33. After demixing and detagging, the isomers were found to have substantially identical (1)H NMR spectra. However, there were some small but reliable...

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Detalhes bibliográficos
Main Authors: Zhang, Kai, Curran, Dennis P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914344/
https://ncbi.nlm.nih.gov/pubmed/20686632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0029-1219376
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