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Asymmetric Synthesis of Methylenetetrahydrofurans by Palladium-Catalyzed [3+2] Cycloaddition of Trimethylenemethane with Aldehydes – A Novel Ligand Design

The palladium-catalyzed [3+2] cycloaddition of trimethylenemethane (TMM) with aldehydes is a direct and efficient route to methylenetetrahydrofurans. Herein we describe the first asymmetric synthesis of methylenetetrahydrofurans utilizing a palladium-TMM complex in the presence of a novel phosphoram...

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Hlavní autoři: Trost, Barry M., Bringley, Dustin A., Silverman, Steven M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097301/
https://ncbi.nlm.nih.gov/pubmed/21513358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja201181g
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