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Segregation of Heterotrimeric G Proteins in Cell Surface Microdomains: G(q) Binds Caveolin to Concentrate in Caveolae, whereas G(i) and G(s) Target Lipid Rafts by Default
Select lipid-anchored proteins such as glycosylphosphatidylinositol (GPI)-anchored proteins and nonreceptor tyrosine kinases may preferentially partition into sphingomyelin-rich and cholesterol-rich plasmalemmal microdomains, thereby acquiring resistance to detergent extraction. Two such domains, ca...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30973/ https://ncbi.nlm.nih.gov/pubmed/11251080 |
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