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Establishment of a Transgenic Mouse Model Specifically Expressing Human Serum Amyloid A in Adipose Tissue

Obesity and obesity co-morbidities are associated with a low grade inflammation and elevated serum levels of acute phase proteins, including serum amyloid A (SAA). In the non-acute phase in humans, adipocytes are major producers of SAA but the function of adipocyte-derived SAA is unknown. To clarify...

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Autors principals: Olsson, Maja, Ahlin, Sofie, Olsson, Bob, Svensson, Per-Arne, Ståhlman, Marcus, Borén, Jan, Carlsson, Lena M. S., Sjöholm, Kajsa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097194/
https://ncbi.nlm.nih.gov/pubmed/21611116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019609
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