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Altering the Ad5 Packaging Domain Affects the Maturation of the Ad Particles
We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain. These novel helper viruses have a significantly delayed viral life cycle and a severe packaging impairment, regardless...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3097180/ https://ncbi.nlm.nih.gov/pubmed/21611162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019564 |
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