Antisense oligodeoxynucleotides targeting ATM strengthen apoptosis of laryngeal squamous cell carcinoma grown in nude mice

BACKGROUND: To conserve laryngeal function and elevate living quality of laryngeal squamous cell carcinoma (LSCC) patients, we designed antisense oligodeoxynucleotides (AS-ODNs) to reduce expression of ATM and to enhance the apoptosis of hep-2 (Human epidermoid laryngeal carcinoma) cells to radiatio...

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Bibliografiska uppgifter
Huvudupphovsmän: Feng, Jun, Zou, Jian, Li, Li, Zhao, Yongsheng, Liu, Shixi
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097000/
https://ncbi.nlm.nih.gov/pubmed/21496344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-43
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