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Antisense inhibition of ATM gene enhances the radiosensitivity of head and neck squamous cell carcinoma in mice
BACKGROUND: Treatment failure after radiotherapy of head and neck squamous cell carcinoma (HNSCC) could be a significant problem. Our objective is to sensitize SCCVII cells to ionizing radiation in vitro and in vivo through inhibiting ATM expression using antisense oligodeoxynucleotides (AS-ODNs), a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584003/ https://ncbi.nlm.nih.gov/pubmed/18950535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-27-56 |
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