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Can phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibition ERase them all?

Seventy percent of breast tumors are estrogen receptor (ER) positive. Although endocrine therapy is successful for the majority of patients with ER-positive tumors, approximately 30% show de novo or acquired resistance and the underlying molecular mechanisms and biomarkers that predict such resistan...

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Detalhes bibliográficos
Main Authors: Meyer, Dominique S, Bentires-Alj, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096967/
https://ncbi.nlm.nih.gov/pubmed/21062517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2718
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