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Silencing of the IKKε gene by siRNA inhibits invasiveness and growth of breast cancer cells

INTRODUCTION: IκB kinase ε (IKKε) is a member of the IKK family that plays an important role in the activation of NF-κB. Overexpressed in more than 30% of breast cancers, IKKε has been recently identified as a potential breast cancer oncogene. The purpose of the present study is to examine the thera...

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Hlavní autoři: Qin, Bin, Cheng, Kun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096963/
https://ncbi.nlm.nih.gov/pubmed/20863366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2644
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