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Binding of the Rett Syndrome Protein, MeCP2, to Methylated and Unmethylated DNA and Chromatin

Methylated CpG Binding Protein 2 (MeCP2) is a nuclear protein named for its ability to selectively recognize methylated DNA. Much attention has been focused on understanding MeCP2 structure and function in the context of its role in Rett syndrome, a severe neurodevelopmental disorder that afflicts o...

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Detalhes bibliográficos
Main Authors: Hansen, Jeffrey C., Ghosh, Rajarshi P., Woodcock, Christopher L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096928/
https://ncbi.nlm.nih.gov/pubmed/21031501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.386
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