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Binding of the Rett Syndrome Protein, MeCP2, to Methylated and Unmethylated DNA and Chromatin

Methylated CpG Binding Protein 2 (MeCP2) is a nuclear protein named for its ability to selectively recognize methylated DNA. Much attention has been focused on understanding MeCP2 structure and function in the context of its role in Rett syndrome, a severe neurodevelopmental disorder that afflicts o...

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Bibliographic Details
Main Authors: Hansen, Jeffrey C., Ghosh, Rajarshi P., Woodcock, Christopher L.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096928/
https://ncbi.nlm.nih.gov/pubmed/21031501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.386
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