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Effect on ex vivo platelet aggregation and in vivo cyclic flow with Na(+)/H(+) exchange inhibition
BIIB 513 and EMD 85131 are selective inhibitors of the Na(+)/H(+) exchanger-1 (NHE-1) that are benzoylguanidine derivatives of the clinically employed diuretic amiloride. Prior studies have suggested a role for NHE-1 activity in platelet activation and aggregation using amiloride or its non-benzoylg...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3096849/ https://ncbi.nlm.nih.gov/pubmed/21082215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11239-010-0530-0 |
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