Activation of CREB in the Nucleus Accumbens Shell Produces Anhedonia and Resistance to Extinction of Fear in Rats

Stress triggers psychiatric conditions including depressive and anxiety disorders. The mechanisms by which stress produces persistent changes in behavior are not fully understood. Here we show in rats that stress (footshock) activates the transcription factor cAMP response element binding protein (C...

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Autori principali: Muschamp, John W., Van't Veer, Ashlee, Parsegian, Aram, Gallo, Miranda S., Chen, Melissa, Neve, Rachael L., Meloni, Edward G., Carlezon, William A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096840/
https://ncbi.nlm.nih.gov/pubmed/21414930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5973-10.2011
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