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Positive Selection of Plasmodium falciparum Parasites With Multiple var2csa-Type PfEMP1 Genes During the Course of Infection in Pregnant Women

Placental malaria infections are caused by Plasmodium falciparum–infected red blood cells sequestering in the placenta by binding to chondroitin sulfate A, mediated by VAR2CSA, a variant of the PfEMP1 family of adhesion antigens. Recent studies have shown that many P. falciparum genomes have multipl...

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Hlavní autoři: Sander, Adam F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten A., Theander, Thor G., Leke, Rose G. F., Lo, Yeung Y., Bobbili, Naveen, Arnot, David E., Taylor, Diane W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096795/
https://ncbi.nlm.nih.gov/pubmed/21592998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir168
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