Positive Selection of Plasmodium falciparum Parasites With Multiple var2csa-Type PfEMP1 Genes During the Course of Infection in Pregnant Women

Placental malaria infections are caused by Plasmodium falciparum–infected red blood cells sequestering in the placenta by binding to chondroitin sulfate A, mediated by VAR2CSA, a variant of the PfEMP1 family of adhesion antigens. Recent studies have shown that many P. falciparum genomes have multipl...

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Bibliografiske detaljer
Main Authors: Sander, Adam F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten A., Theander, Thor G., Leke, Rose G. F., Lo, Yeung Y., Bobbili, Naveen, Arnot, David E., Taylor, Diane W.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096795/
https://ncbi.nlm.nih.gov/pubmed/21592998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir168
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