Positive Selection of Plasmodium falciparum Parasites With Multiple var2csa-Type PfEMP1 Genes During the Course of Infection in Pregnant Women

Placental malaria infections are caused by Plasmodium falciparum–infected red blood cells sequestering in the placenta by binding to chondroitin sulfate A, mediated by VAR2CSA, a variant of the PfEMP1 family of adhesion antigens. Recent studies have shown that many P. falciparum genomes have multipl...

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Detalhes bibliográficos
Main Authors: Sander, Adam F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten A., Theander, Thor G., Leke, Rose G. F., Lo, Yeung Y., Bobbili, Naveen, Arnot, David E., Taylor, Diane W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096795/
https://ncbi.nlm.nih.gov/pubmed/21592998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir168
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