Plasmodium falciparum Associated with Severe Childhood Malaria Preferentially Expresses PfEMP1 Encoded by Group A var Genes

Parasite-encoded variant surface antigens (VSAs) like the var gene–encoded Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family are responsible for antigenic variation and infected red blood cell (RBC) cytoadhesion in P. falciparum malaria. Parasites causing severe malaria in nonimmu...

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Main Authors: Jensen, Anja T.R., Magistrado, Pamela, Sharp, Sarah, Joergensen, Louise, Lavstsen, Thomas, Chiucchiuini, Antonella, Salanti, Ali, Vestergaard, Lasse S., Lusingu, John P., Hermsen, Rob, Sauerwein, Robert, Christensen, Jesper, Nielsen, Morten A., Hviid, Lars, Sutherland, Colin, Staalsoe, Trine, Theander, Thor G.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211911/
https://ncbi.nlm.nih.gov/pubmed/15123742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040274
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