Role for Stromal Heterogeneity in Prostate Tumorigenesis

Prostate cancer develops through a stochastic mechanism whereby pre-cancerous lesions on occasion progress to multifocal adenocarcinoma. Analysis of human benign and cancer prostate tissues revealed heterogeneous loss of TGF-β signaling in the cancer associated stromal fibroblastic cell compartment....

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Autors principals: Kiskowski, Maria A., Jackson, Roger S., Banerjee, Jheelam, Li, Xiaohong, Kang, Minchul, Iturregui, Juan M., Franco, Omar E., Hayward, Simon W., Bhowmick, Neil A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096737/
https://ncbi.nlm.nih.gov/pubmed/21444670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2999
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