Prostate tumor progression is mediated by a paracrine TGF-β/Wnt3a signaling axis

TGF-β is an important paracrine factor in tumorigenesis. Ligand binding of the type I and II TGF-β receptors initiate downstream signaling. The role of stromal TGF-β signaling in prostate cancer progression is unknown. In mice the conditional stromal knockout of the TGF-β receptor type II expression...

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Detalhes bibliográficos
Main Authors: Li, Xiaohong, Placencio, Veronica, Iturregui, Juan M., Uwamariya, Consolate, Sharif-Afshar, Ali-Reza, Koyama, Tatsuki, Hayward, Simon W., Bhowmick, Neil A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222150/
https://ncbi.nlm.nih.gov/pubmed/18724388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.293
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