Adenoma Formation following Limited Ablation of p120-Catenin in the Mouse Intestine

p120 loss destabilizes E-cadherin and could therefore result in tumor and/or metastasis-promoting activities similar to those caused by E-cadherin downregulation. Previously, we reported that p120 is essential in the intestine for barrier function, epithelial homeostasis and survival. Conditional p1...

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Main Authors: Smalley-Freed, Whitney G., Efimov, Andrey, Short, Sarah P., Jia, Peilin, Zhao, Zhongming, Washington, M. Kay, Robine, Sylvie, Coffey, Robert J., Reynolds, Albert B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096651/
https://ncbi.nlm.nih.gov/pubmed/21611205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019880
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