Targeted Skipping of Human Dystrophin Exons in Transgenic Mouse Model Systemically for Antisense Drug Development

Antisense therapy has recently been demonstrated with great potential for targeted exon skipping and restoration of dystrophin production in cultured muscle cells and in muscles of Duchenne Muscular Dystrophy (DMD) patients. Therapeutic values of exon skipping critically depend on efficacy of the dr...

Full description

Saved in:
Bibliographic Details
Main Authors: Wu, Bo, Benrashid, Ehsan, Lu, Peijuan, Cloer, Caryn, Zillmer, Allen, Shaban, Mona, Lu, Qi Long
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096650/
https://ncbi.nlm.nih.gov/pubmed/21611204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019906
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items